This week’s reproductive literature links three levels of care: guidelines, population burden, and survivorship implementation. The International Menopause Society published recommendations and key messages that emphasize standardized midlife care—useful for harmonizing counseling, MHT decisions, and risk-based evaluation in everyday practice. [1]
A Global Burden of Disease analysis quantified endometriosis, PCOS, and unexplained infertility and their attribution to infertility over time and geography—shaping where health systems should prioritize diagnostics and access. [2]
A pediatric cancer survivorship oncofertility paper highlights gaps in fertility assessment and evaluation of reproductive dysfunction—an implementation reminder that survivorship endocrine care needs measurable checkpoints, not just referral intentions. [3]
Practical “tactics” to consider now:
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Standardize menopause visits (symptom inventory, contraindication screening, cardiometabolic assessment, shared decision-making documentation).
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Use burden data to justify capacity (endo/PCOS pathways, infertility services, multidisciplinary clinics).
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Build survivorship triggers: automatic fertility-risk stratification and referral timing, rather than ad hoc recognition.
References
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Panay N, Fenton A, Hamoda H, et al; IMS Publication Steering Committee and The IMS Recommendations Writing Group. International Menopause Society (IMS) recommendations and key messages on women’s midlife health and menopause. Climacteric. 2025;28(6):634-656. https://doi.org/10.1080/13697137.2025.2585487
PubMed: https://pubmed.ncbi.nlm.nih.gov/41433054/ -
Xu Y, Jia Y, Li Q, et al. Global, regional, and national burden of endometriosis, PCOS, and unexplained infertility and their attribution to infertility, 1990-2021: Global Burden of Disease Study 2021. J Evid Based Med. 2025;:e70100. https://doi.org/10.1111/jebm.70100
PubMed: https://pubmed.ncbi.nlm.nih.gov/41437663/ -
Sarangarajan S, Singh SD, Singh A, et al. Bridging gaps in oncofertility: evaluation of reproductive dysfunction and fertility assessment in pediatric cancer survivors. Support Care Cancer. 2025;34(1):57. https://doi.org/10.1007/s00520-025-10284-4
PubMed: https://pubmed.ncbi.nlm.nih.gov/41455091/